Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure
Purpose
Gastric Bypass followed by renal transplantation is superior to medical management followed by renal transplant for patients with severe obesity and renal failure.
Conditions
- Severe Obesity
- Renal Failure
Eligibility
- Eligible Ages
- Between 18 Years and 59 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Body mass index 40-55 kg/m2 - Age less than 60 years - Available support person - Adequate insurance - All other criteria required for renal transplantation
Exclusion Criteria
- Schizophrenia - Bipolar disorder - Crohn's disease - Human Immunodeficiency Virus - Cirrhosis - Prior weight loss surgery - Prior mesh hernia repair - Prior anti-reflux surgery - Inability to walk 200 feet - Significant coronary disease - Significant lung disease - Fixed expiratory volume 1 less than 75% or on oxygen - Addiction to alcohol or drugs - Inability to quit smoking - Jehovah's witness - Non-compliance with dialysis regimen - Previous renal transplant - Non-English speaking
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Surgical Gastric Bypass |
Patients will undergo surgical gastric bypass according to standard institutional protocols |
|
|
Experimental Medical Weight Loss Management |
Patients will receive best practices medical management for weight loss under current institutional protocols |
|
More Details
- Status
- Active, not recruiting
- Sponsor
- Vanderbilt University Medical Center