Quantitation of Glymphatic Functioning in Sleep and Meditative States
Purpose
This involves development and application of magnetic resonance imaging (MRI) methods for visualizing hemodynamic and metabolic relationships in healthy volunteers with advanced meditation experience.
Conditions
- Parkinson Disease
- Sleep
Eligibility
- Eligible Ages
- Between 18 Years and 45 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Ages 14-45 - "Adept meditator status"
Exclusion Criteria
- Any non-MR compatible material implant, or contraindication to MR scanning - Claustrophobia or inability to lie still for prolonged periods of time - Participants with a recent (less than 2 months) infection, tattoo, or wound - No consumption of stimulants or alcohol within 12 hours of the study visit - clinical diagnosis of any major neurological or psychological condition - Taking benzodiazepines, cholinestorase inhibitors, anti-psychotics, opioids, MAO inhibitors
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Basic Science
- Masking
- None (Open Label)
- Masking Description
- no masking is used in this protocol
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Adept Meditators |
Subjects will undergo scanning during awake, sleep deprived, and meditative states of consciousness. |
|
Recruiting Locations
Vanderbilt University Medical Center
Nashville, Tennessee 37212-3160
Nashville, Tennessee 37212-3160
More Details
- Status
- Recruiting
- Sponsor
- Vanderbilt University Medical Center
Detailed Description
This study is evaluating the glymphatic system during awake, sleep, and meditative states.