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Thank you for your interest in Vanderbilt research! Taking part in research is one way to be part of tomorrow’s health care discoveries. Vanderbilt is always looking for volunteers just like you so that our researchers can better understand how to prevent, diagnose, and treat diseases. Everyone is needed. Both healthy volunteers and people with health conditions can help us answer important questions that impact the health of our communities. Ready to start searching for a study?
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- Click on the study titles for information.
- Click on Contact/Details tab to get information for contacting the study team.
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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD1
Atherosclerotic Cardiovascular Disease
End Stage Kidney Disease
Atherosclerotic Cardiovascular Disease in Patients With ESKD
This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized,
double-blind, placebo-controlled study. Part 1 (phase 2b) is a dose-finding study for
CSL300 vs placebo. Part 2 (phase 3) aims to assess the efficacy of CSL300 on
cardiovascular (CV) outcomes and safety in subjects1 expand
This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study. Part 1 (phase 2b) is a dose-finding study for CSL300 vs placebo. Part 2 (phase 3) aims to assess the efficacy of CSL300 on cardiovascular (CV) outcomes and safety in subjects with systemic inflammation and either atherosclerotic cardiovascular disease (ASCVD) or diabetes with end stage kidney disease (ESKD) undergoing maintenance dialysis. Type: Interventional Start Date: Oct 2022 |