Purpose

RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing tissue samples from patients with head and neck cancer and from healthy participants.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Criteria


DISEASE CHARACTERISTICS:

- Meets 1 of the following criteria:

- Diagnosis of head and neck cancer

- Being treated at Vanderbilt University Medical Center for the cancer

- Healthy participant

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- Not specified

Study Design

Phase
Study Type
Observational [Patient Registry]
Observational Model
Cohort
Time Perspective
Cross-Sectional

Arm Groups

ArmDescriptionAssigned Intervention
Healthy Volunteers Non-tumor volunteers will be asked to participate at the time that they are attending a head and neck cancer screening clinic or at the time they are accompanying a patient to their appointment at the head and neck clinic. Intake sheets and biological specimens contributed by volunteers will be coded at the time of collection so that no identifiers are obtained. These specimens will not be linked to identifiers.
  • Other: biologic sample preservation procedure
  • Other: medical chart review
Head and Neck Tumor patients Eligible patients will be identified at the Vanderbilt Head & Neck Clinic by clinical and research staff. An appropriately trained staff member will discuss the protocol with the patient (including, risks, benefits, alternatives, etc.).
  • Other: biologic sample preservation procedure
  • Other: medical chart review

Recruiting Locations

Vanderbilt-Ingram Cancer Center
Nashville, Tennessee 37232-6838
Contact:
Clinical Trials Office - Vanderbilt-Ingram Cancer Center
800-811-8480

Vanderbilt-Ingram Cancer Center - Cool Springs
Nashville, Tennessee 37064
Contact:
Kim Young
800-811-8480

Vanderbilt-Ingram Cancer Center at Franklin
Nashville, Tennessee 37064
Contact:
Kim Young, MD
800-811-8480

More Details

Status
Recruiting
Sponsor
Vanderbilt University Medical Center

Study Contact

Brandee Brown
615-936-4896
brandee.t.brown@vumc.org

Detailed Description

OBJECTIVES: - Maintain and update a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer. - Develop a repository of biospecimens from these patients. OUTLINE: Tumor tissue samples and/or bronchial washings are collected from patients undergoing planned surgery and/or bronchoscopy, respectively. Buccal swabs and/or mouthwash samples and saliva samples are collected. Patients also undergo blood sample collection at baseline and then every 2-6 months thereafter. Healthy participants contribute blood samples, buccal swabs, and mouthwash samples at baseline only. Information about medical and family history and cancer risk factors is also collected. PROJECTED ACCRUAL: No limit. FOLLOW UP: Indefinite, until date of death or lost to follow up.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.