Vanderbilt Clinical Trials

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Vanderbilt conducts research studies and clinical trials in various divisions throughout the Medical Center. We know that figuring out where to start can be one of the biggest obstacles a volunteer faces when searching for research study opportunities.

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459 matching studies

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Hybrid L24 New Enrollment Post Approval Study Cochlear High Frequency Sensorineural Hearing Loss This study evaluates the long term safety and effectiveness of the Nucleus Hybrid L24 Implant in a group of newly implanted adults. expand This study evaluates the long term safety and effectiveness of the Nucleus Hybrid L24 Implant in a group of newly implanted adults. Type: Interventional Start Date: Feb 2015 open study
A Study to Evaluate the Safety, Tolerability, and Activity of KD025 in Subjects With Chronic Graft Versus... Kadmon Corporation, LLC Graft vs Host Disease This study is being conducted to evaluate the safety, tolerability, and activity of KD025 in adult subjects with chronic Graft versus Host Disease (cGVHD). expand This study is being conducted to evaluate the safety, tolerability, and activity of KD025 in adult subjects with chronic Graft versus Host Disease (cGVHD). Type: Interventional Start Date: Aug 2016 open study
Hepatocellular Research Registry Vanderbilt University Hepatocytes This is a registry of human hepatocytes (liver cells) for research purposes. expand This is a registry of human hepatocytes (liver cells) for research purposes. Type: Observational Start Date: Apr 2004 open study
Hormonal, Metabolic, and Signaling Interactions in PAH Vanderbilt University Idiopathic Pulmonary Arterial Hypertension Heritable Pulmonary Arterial Hypertension Scleroderma Associated Pulmonary Arterial Hypertension Appetite Suppressant Associate PAH Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease. expand Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease. Type: Observational Start Date: Sep 2012 open study
A Prospective, Multi-center Registry for Patients With Short Bowel Syndrome Shire Short Bowel Syndrome This is a global prospective, observational, multi-center registry to evaluate the long-term safety profile for patients with short bowel syndrome (SBS) who are treated with teduglutide in a routine clinical setting. The registry will also evaluate the long-term clinical outcomes... expand This is a global prospective, observational, multi-center registry to evaluate the long-term safety profile for patients with short bowel syndrome (SBS) who are treated with teduglutide in a routine clinical setting. The registry will also evaluate the long-term clinical outcomes in patients with SBS. SBS patients treated and not treated with teduglutide will be enrolled. Type: Observational [Patient Registry] Start Date: Jun 2014 open study
Exercise in Genetic Cardiovascular Conditions Yale University Hypertrophic Cardiomyopathy Long QT Syndrome The goal is to determine how lifestyle and exercise impact the well-being of individuals with hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS). expand The goal is to determine how lifestyle and exercise impact the well-being of individuals with hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS). Type: Observational [Patient Registry] Start Date: May 2015 open study
Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis University of Pittsburgh Dermatomyositis Polymyositis The purpose of this multi-center pilot study is to determine if the drug tocilizumab (Actemra) is effective in the treatment of patients with refractory adult polymyositis (PM) and dermatomyositis (DM). expand The purpose of this multi-center pilot study is to determine if the drug tocilizumab (Actemra) is effective in the treatment of patients with refractory adult polymyositis (PM) and dermatomyositis (DM). Type: Interventional Start Date: Oct 2014 open study
Timing of Inguinal Hernia Repair in Premature Infants Vanderbilt University Inguinal Hernia Premature Birth of Newborn The purpose of this study is to determine whether early (before NICU discharge) or late (55-60 weeks post-menstrual age) inguinal hernia repair is safer for premature infants who have an inguinal hernia. expand The purpose of this study is to determine whether early (before NICU discharge) or late (55-60 weeks post-menstrual age) inguinal hernia repair is safer for premature infants who have an inguinal hernia. Type: Interventional Start Date: Jun 2013 open study
Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer ECOG-ACRIN Cancer Research Group Localized Urothelial Carcinoma of the Renal Pelvis and Ureter Recurrent Urothelial Carcinoma of the Renal Pelvis and Ureter Regional Urothelial Carcinoma of the Renal Pelvis and Ureter This phase II trial studies how well giving chemotherapy before surgery works in treating patients with aggressive upper urinary tract cancer. Drugs used in chemotherapy, such as methotrexate, vinblastine, doxorubicin hydrochloride, cisplatin, gemcitabine hydrochloride, and carboplatin,... expand This phase II trial studies how well giving chemotherapy before surgery works in treating patients with aggressive upper urinary tract cancer. Drugs used in chemotherapy, such as methotrexate, vinblastine, doxorubicin hydrochloride, cisplatin, gemcitabine hydrochloride, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Removing the affected upper urinary tract by surgery is the recommended treatment for upper urinary tract cancer, but can cause loss of kidney function and prevent patients from being able to receive chemotherapy after surgery. Giving chemotherapy before surgery, when the kidneys are working at their maximum, may allow less tissue to be removed during surgery and may be more effective in treating patients with high grade upper urinary tract cancer. Type: Interventional Start Date: Apr 2015 open study